Immunohistochemical analysis of non-Hodgkin's lymphomas with the monoclonal antibody to follicular center lymphocytes reactive in paraffin sections.
Article
in English
| IMSEAR
| ID: sea-40475
ABSTRACT
The monoclonal antibody designated LN-1 was used in an attempt to identify the antigen in follicular center cell lymphomas using tissue sections fixed in formalin. The LN-1 antibody has been shown in previous studies to identify follicular center cells and give reproducible results in tissue fixed in B5. We used the ABC peroxidase technique to examined formalin-fixed, paraffin embedded sections representing 52 cases of various histologic subgroups of non-Hodgkin's lymphomas based upon the Lukes-Collins classification. Following immunostaining with LN-1 using overnight incubation of the antibody and papain treated sections, 37 cases, and all of the 38 cases previously diagnosed as follicular center cell lymphomas, gave a positive reaction to the LN-1 monoclonal antibody.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Paraffin
/
Lymphoma, Non-Hodgkin
/
Humans
/
B-Lymphocytes
/
Cell Division
/
Immunoenzyme Techniques
/
Antibodies, Monoclonal
Type of study:
Prognostic study
Language:
English
Year:
1989
Type:
Article
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