Factors determining the severity of pulmonary function impairment in silicotic patients.
Article
in English
| IMSEAR
| ID: sea-41329
ABSTRACT
OBJECTIVE:
Silicosis is the most common occupational lung disease in Thailand. Determinants of pulmonary function impairment in Thai silicotic patients have not been mentioned before. MATERIAL ANDMETHOD:
The present study was conducted in silicotic patients who attended the Siriraj Occupational Lung Clinic in the year 2006. Patients were classified according to the forced expiratory volume in one second (FEV1) into the severe impairment group (< 50% predicted) and the non-severe group (FEV1 > 50% predicted) which includes normal FEV1. Comparison between the two groups in terms of demographic characteristics, smoking history, history of pulmonary tuberculosis, and radiographic features were assessed.RESULTS:
Thirty-four patients of which 24 were female (70.6%) had an overall mean age of 53.7 years. Seven patients (20.6%) had severe impairment, four were female, three were smokers, and two had a history of pulmonary tuberculosis. All of the severe impairment patients had nodule profusion in category 2 and had large opacity. Only the presence of large opacity was significantly associated with the severity of pulmonary function impairment (p = 0.002).CONCLUSION:
Only the presence of large opacity in a chest radiograph can determine the severity of pulmonary function impairment in Thai silicotic patients.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Respiratory Function Tests
/
Silicosis
/
Thailand
/
Aged
/
Female
/
Humans
/
Male
/
Cross-Sectional Studies
/
Disease Progression
/
Adult
Type of study:
Observational study
/
Prevalence study
/
Prognostic study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Year:
2007
Type:
Article
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