Efficacy of cellulose triacetate dialyzer and polysulfone synthetic hemofilter for continuous venovenous hemofiltration in acute renal failure.
Article
in English
| IMSEAR
| ID: sea-41626
ABSTRACT
OBJECTIVE:
To compare the clearance performances and biocompatibility between the modified cellulose membrane and the standard synthetic membrane in continuous renal replacement therapy (CRRT). MATERIAL ANDMETHOD:
Seventeen patients with acute renal failure (ARF) were treated with separated continuous veno venous hemofiltration (CVVH) system conducted with the pre-dilution mode. The modified cellulose used was a Sureflux150E (cellulose triacetate) and the standard synthetic membranes used was an AV-400. Blood and replacement flow rate were kept at 100 and 20 mL/min, respectively. Ultrafiltraion rate was 1,200 mL/hr. Samplings of blood and ultrafiltrate were collected at baseline, 2, 8, 16, and 24 hr.RESULTS:
Patients in both methods could similarly tolerate CRRT with only minor complications. Sureflux 150E and AV-400 provided comparable values of sieving coefficients and clearances of small solutes. The albumin loss in ultrafiltrate by Sureflux 150E was greater than AV-400. The values of life span and biocompatability of both hemofilters were not different.CONCLUSION:
Because of the excellent efficacy and the much cheaper cost, the modified cellulose membrane could be an appropriate alternative to standard synthetic membrane in CRRT.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Polymers
/
Sulfones
/
Urea
/
Uric Acid
/
Female
/
Humans
/
Male
/
Serum Albumin
/
Cellulose
/
Prospective Studies
Type of study:
Controlled clinical trial
/
Observational study
Language:
English
Year:
2006
Type:
Article
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