Maintenance therapy with itraconazole after treatment of cryptococcal meningitis in the acquired immunodeficiency syndrome.
Article
in English
| IMSEAR
| ID: sea-41974
ABSTRACT
We conducted a prospective, open trial to establish the efficacy of itraconazole 400 mg/d as maintenance treatment for cryptococcal meningitis in AIDS patients. Between February 1996 and May 1997, 50 patients were included for analysis. After a mean follow-up of 326 days, 2 of 38 patients (5.3 per cent) had relapses of symptomatic cryptococcal meningitis. Hepatotoxicity occurred in 2 cases. In conclusion, maintenance therapy with itraconazole 400 mg/d is effective in preventing recurrent cryptococcal meningitis.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Recurrence
/
Female
/
Humans
/
Male
/
Prospective Studies
/
Meningitis, Cryptococcal
/
AIDS-Related Opportunistic Infections
/
Itraconazole
/
Adult
/
Antifungal Agents
Type of study:
Observational study
Language:
English
Year:
1997
Type:
Article
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