Multidrug-resistant tuberculosis: response to treatment.
Article
in English
| IMSEAR
| ID: sea-42012
ABSTRACT
OBJECTIVE:
We investigated clinical response and mortality rates in 18 HIV- negative patients with multidrug-resistant tuberculosis.METHOD:
We obtained detailed data from our hospital on patients with multidrug - resistant tuberculosis defined as tuberculosis resistant at least to isoniazid and rifampicin. Therapeutic responses were evaluated by both microbiologic and clinical data.RESULTS:
From January 1985 to December 1990, 18 HIV-negative patients were identified and treated. One patient committed suicide 1 week after receiving antituberculous drugs. Of the 17 patients, 10 (58.8%) had clinical response as well as microbiologic response, 6 (35.3%) were persisters during 24 months of follow-up, and 1 (5.8%) died after 30 months of treatment. The median follow-up for the patients was 87 weeks (range, 24 to 212). For those who responded well, there was no relapse.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thailand
/
Tuberculosis, Pulmonary
/
Female
/
Humans
/
Male
/
Adolescent
/
Treatment Outcome
/
Tuberculosis, Multidrug-Resistant
/
HIV Seronegativity
/
Adult
Country/Region as subject:
Asia
Language:
English
Year:
1996
Type:
Article
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