Antifungal drug combinations for Cryptococcus neoformans and Prototheca spp.
Article
in English
| IMSEAR
| ID: sea-42220
ABSTRACT
Seventy-one isolates of Cryptococcus neoformans and 5 isolates of Prototheca spp. were tested for in vitro susceptibility against amphotericin B alone and against the combination of amphotericin B with each clinically relevant concentration of flucytosine (5-FC) and rifampin by broth dilution methods. The combinations of amphotericin B and rifampin produced greater effect on reduction of the minimal inhibition concentration (MIC) of amphotericin B than did either drug used individually. Flucytosine combined with amphotericin B produced little or no reduction of the MIC compared with amphotericin B alone.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Prototheca
/
Humans
/
Microbial Sensitivity Tests
/
Amphotericin B
/
Sensitivity and Specificity
/
Cryptococcus neoformans
/
Drug Therapy, Combination
/
Flucytosine
/
Antifungal Agents
Type of study:
Diagnostic study
Language:
English
Year:
2000
Type:
Article
Similar
MEDLINE
...
LILACS
LIS