The development and validation of a diabetes risk score for high-risk Thai adults.
Article
in English
| IMSEAR
| ID: sea-42250
ABSTRACT
OBJECTIVE:
To develop a simple risk score to identify high-risk individuals for diabetes screening in Thailand. MATERIAL ANDMETHOD:
The authors analyzed data from 75-g oral glucose tolerance tests performed in 159 males and 270 females, aged 48.4 +/- 10.9 years.RESULTS:
The independent variables associated with diabetes included age (p < 0.001), BMI (p < 0.01) and known history of hypertension (HHT) (p < 0.01). The risk equation was Y = 3 age + 5 BMI + 50 HHT. At the cut-off Y value of 240, the sensitivity and specificity for having diabetes were 96.8% and 24.0%, respectively. The positive predictive value was 17.8% and the negative predictive value was 97.8%. Using the equation in a validation group comprising 1617 subjects, it was found that 560 (34.6%) diabetes screenings could be saved while 28 subjects (12.8%) with diabetes would be missed.CONCLUSION:
The authors have developed a simple risk scoring method that should be helpful in decreasing the number of unnecessary screening and optimizing the costs associated with diabetes screening.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thailand
/
Female
/
Humans
/
Male
/
Mass Screening
/
Risk Factors
/
ROC Curve
/
Health Status Indicators
/
Sensitivity and Specificity
/
Risk Assessment
Type of study:
Diagnostic study
/
Etiology study
/
Prognostic study
/
Screening study
Country/Region as subject:
Asia
Language:
English
Year:
2007
Type:
Article
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