Efficacy of benzimidazole carbamate on an intestinal fluke co-infected with nematodes.
Article
in English
| IMSEAR
| ID: sea-42270
ABSTRACT
The efficacy of a single dose of benzimidazole, drugs commonly used for the treatment of Ascaris and hookworm, was evaluated against one of the tiny-sized intestinal flukes, Haplorchis sp in the endemic area where mixed infections of roundworms and flatworms existed. At day 7 after treatment, albendazole (400 mg) induced 42.5% cure rate, mebendazole (500 mg) a cure rate of 32.4%, on the other hand, praziquantel (40 mg/kg) gave 94.6% cure rate and the placebo at 15.9%. At the single dose, benzimidazole could not completely expelled the haplorchid; but could reduce one third to two fifth of the infection, similar to the drugs efficacy against Trichuris infection.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Praziquantel
/
Thailand
/
Benzimidazoles
/
Humans
/
Albendazole
/
Treatment Outcome
/
Helminthiasis
/
Intestinal Diseases, Parasitic
/
Mebendazole
/
Anthelmintics
Type of study:
Controlled clinical trial
Country/Region as subject:
Asia
Language:
English
Year:
2005
Type:
Article
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