HLA antigens in Indian population with non-specific aortoarteritis.
Indian Heart J
;
1990 Mar-Apr; 42(2): 85-7
Article
in English
| IMSEAR
| ID: sea-4275
ABSTRACT
HLA typing of Class I antigens (HLA - A & -B loci) was done for 65 patients suffering from nonspecific aortoarteritis, in Indian population. The diagnosis of these patients was based on clinical findings and confirmed by angiographic studies. Decreased phenotype frequency of HLA-A19 (p less than 0.005, relative risk 0.28), increased frequency of HLA-B5 (p less than 0.005, relative risk 2.46) and B21 (p less than 0.005, relative risk 3.25) was observed when compared with the control group. A decreased frequency of two other alleles of B locus i.e. B35 (p less than 0.005, relative risk 0.27) and B40 (p less than 0.05, relative risk 0.04) was seen in patient group as compared to control. The data indicate the possible association of HLA-B5 and B21 antigens with the nonspecific aortoarteritis.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Aortic Arch Syndromes
/
Phenotype
/
Autoimmune Diseases
/
Humans
/
HLA-A Antigens
/
HLA-B Antigens
/
Child
/
Risk Factors
/
Adolescent
/
Adult
Type of study:
Etiology study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Journal:
Indian heart j
Year:
1990
Type:
Article
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