Use of Hachinski Ischemic Score in the memory clinic: Thai experience.
Article
in English
| IMSEAR
| ID: sea-42756
ABSTRACT
BACKGROUND:
The validity ofHachinski Ischemic Score (HIS) in differentiating between Alzheimer's disease (AD) and Vascular dementia (VaD) has been questioned and compared with the gold standard autopsy.OBJECTIVE:
To confirm that the HIS can be used to differentiate related VaD from AD in a Thai population. MATERIAL ANDMETHOD:
A prospective study of 398 patients who were attending the Memory Clinic, at Siriraj Hospital between January 2001 and October 2003.RESULTS:
The 214 patients, with a mean age of 71.15 + 10.20 years, were classified as AD, VaD or mixed dementia (AD with cerebrovascular disease) in proportion of 60.2%, 30.4%, and 9.3% respectively. The authors propose HIS at 5 as a cut off point to differentiate patients with AD and those with VaD or AD with cerebrovascular disease with sensitivity of 85.3% and specificity of 72.9%.CONCLUSION:
The HIS can be applied to differentiate dementia related vascular etiology from AD in a Thai population.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thailand
/
Aged, 80 and over
/
Aged
/
Female
/
Humans
/
Male
/
Dementia, Vascular
/
Prospective Studies
/
Sensitivity and Specificity
/
Diagnosis, Differential
Type of study:
Diagnostic study
/
Observational study
Limits:
Aged80
Country/Region as subject:
Asia
Language:
English
Year:
2006
Type:
Article
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