Drug-induced agranulocytosis.
Article
in English
| IMSEAR
| ID: sea-43067
ABSTRACT
Forty cases of drug-induced agranulocytosis from the Department of Medicine, Faculty of Medicine, Chiang Mai University during the 12 year period 1975-1987 were analysed. In 32 cases, the related etiologic drugs were identified. These were thiacetazone and isoniazid in 10 cases (25%), propylthiouracil in 6 cases (15%) sulfa drugs in 5 cases (12.5%) combination of analgesic and antibiotics in 3 cases (7.5%), anti-psychotic in 2 cases (5%), antibiotics in 5 cases including, ampicillin (2 cases) and others (3 cases), and ether in 1 case (2.5%). The other 8 cases (20%) received unknown drugs from private clinics. Twenty-four cases had complete recovery in 13-14 days after withdrawal of the incriminating drugs, and sixteen cases (40%) died with septicemia.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thailand
/
Aged
/
Female
/
Humans
/
Male
/
Child
/
Retrospective Studies
/
Adolescent
/
Adult
/
Agranulocytosis
Type of study:
Observational study
Country/Region as subject:
Asia
Language:
English
Year:
1989
Type:
Article
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