Chlamydia pneumoniae in community-acquired pneumonia.
Article
in English
| IMSEAR
| ID: sea-43563
ABSTRACT
Chlamydia pneumoniae has been established recently as an important human respiratory pathogen. The aim of this study was to define the prevalence of C. pneumoniae in community-acquired pneumonia. We prospectively investigated adult patients who were treated as inpatients and outpatients. Acute and convalescent serum samples were obtained from each patient. Serological diagnosis of C. pneumoniae infection was determined by enzyme-linked immunosorbent assay (ELISA). Eighty paired sera were tested for C. pneumoniae-specific IgM, IgG and IgA. Twenty-one patients (26.2%) had serological results compatible with acute C. pneumoniae infection. Eighteen (85.7%) of these infected patients were C. pneumoniae-specific IgM positive, three had a seroconversion of IgA and two had a four-fold or greater increase in C. pneumoniae-specific IgG antibody titer. The most common clinical manifestations of community-acquired pneumonia due to C. pneumoniae were fever (100%), cough (100%), chest pain (47.6%) and shortness of breath (42.9%). Physical examination revealed crackle in 85.7 per cent of the cases. These findings suggest that C. pneumoniae is a common cause of community-acquired pneumonia in Thailand.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thailand
/
Aged, 80 and over
/
Aged
/
Female
/
Humans
/
Male
/
Enzyme-Linked Immunosorbent Assay
/
Serologic Tests
/
Chlamydia Infections
/
Incidence
Type of study:
Diagnostic study
/
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Aged80
Country/Region as subject:
Asia
Language:
English
Year:
2001
Type:
Article
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