The use of levonorgestrel - IUD in the treatment of uterine myoma in Thai women.
Article
in English
| IMSEAR
| ID: sea-44305
ABSTRACT
OBJECTIVE:
This study was designed to evaluate the potential usefulness of the levonorgestrel-releasing intrauterine device (LNG - IUD ; Mirena) in treating women with uterine myomas.DESIGN:
Prospective before-and-after (comparing) study.SETTING:
Department of Obstetrics and Gynecology King Chulalongkorn Memorial Hospital.SUBJECTS:
Sixteen women with uterine myomas who intended to receive treatment with the LNG IUD. INTERVENTION(S) Clinical and ultrasound examinations were performed prior to and at 1, 3 and 6 months after the LNG IUD insertion. MAIN OUTCOMEMEASURES:
Myoma and Uterine volume, menstrual blood loss assessed with pictorial blood loss assessment charts and hematocrit.RESULTS:
Use of the LNG IUD was associated with a statistically significant reduction in the total myoma volume, average uterine size and marked reduction in menstrual blood loss. After 6 months of use, the median total myoma volume decreased from 19.82 mL to 11.63 mL (p < 0.05), median pictorial blood loss assessment chart score declined from 89 to 3 (p < 0.05). Hematocrit level increased over 6 months of use. The most common side effects were bleeding disturbances (68.8%). No pregnancies occurred during the study.CONCLUSION:
The LNG IUD was associated with a profound reduction in myoma and uterine volume. For women with myomas of this size, the LNG IUD provides effective medical treatment of bleeding.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thailand
/
Time Factors
/
Uterine Neoplasms
/
Uterus
/
Female
/
Humans
/
Prospective Studies
/
Levonorgestrel
/
Contraceptives, Oral, Synthetic
/
Adult
Type of study:
Observational study
Country/Region as subject:
Asia
Language:
English
Year:
2006
Type:
Article
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