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Distribution of HLA-A and B antigens in northeastern-Thais.
Article in English | IMSEAR | ID: sea-44482
ABSTRACT
The phenotype and gene frequencies of HLA class I were studied in the Northeastern Thai population. Blood samples were collected from 100 unrelated healthy Northeastern Thais. HLA-A and B antigens were typed by using the standard microlymphocytotoxicity test. Twelve HLA-A and twenty-five HLA-B antigens were found in this population. HLA-A2, A24, A11 and the HLA-B46, B15, B22 antigens are commonly found in this group. Linkage disequilibrium analysis indicated the existence of fifteen haplotypes. The HLA-A2, B46 haplotype was the most common. These results will be useful for further studies in anthropology, organ transplantation and MHC associated disease in Northeastern Thais.
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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Phenotype / Rural Population / Thailand / Humans / Histocompatibility Testing / T-Lymphocytes / HLA-A Antigens / HLA-B Antigens / Linkage Disequilibrium / Gene Frequency Country/Region as subject: Asia Language: English Year: 1996 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Phenotype / Rural Population / Thailand / Humans / Histocompatibility Testing / T-Lymphocytes / HLA-A Antigens / HLA-B Antigens / Linkage Disequilibrium / Gene Frequency Country/Region as subject: Asia Language: English Year: 1996 Type: Article