Distribution of HLA-A and B antigens in northeastern-Thais.
Article
in English
| IMSEAR
| ID: sea-44482
ABSTRACT
The phenotype and gene frequencies of HLA class I were studied in the Northeastern Thai population. Blood samples were collected from 100 unrelated healthy Northeastern Thais. HLA-A and B antigens were typed by using the standard microlymphocytotoxicity test. Twelve HLA-A and twenty-five HLA-B antigens were found in this population. HLA-A2, A24, A11 and the HLA-B46, B15, B22 antigens are commonly found in this group. Linkage disequilibrium analysis indicated the existence of fifteen haplotypes. The HLA-A2, B46 haplotype was the most common. These results will be useful for further studies in anthropology, organ transplantation and MHC associated disease in Northeastern Thais.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Phenotype
/
Rural Population
/
Thailand
/
Humans
/
Histocompatibility Testing
/
T-Lymphocytes
/
HLA-A Antigens
/
HLA-B Antigens
/
Linkage Disequilibrium
/
Gene Frequency
Country/Region as subject:
Asia
Language:
English
Year:
1996
Type:
Article
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