Acarboxy prothrombin (PIVKA-II) in cord plasma in the south of Thailand.
Article
in English
| IMSEAR
| ID: sea-44515
ABSTRACT
Acarboxy prothrombin or PIVKA-II (protein induced by vitamin K absence or antagonist-II) was used to determine the presence of vitamin deficiency in newborn infants. Of 230 cord blood samples assayed by using ELISA method, 34.8 per cent were positive for PIVKA-II 0.13-17 AU/ml. The positive rate for PIVKA-II was greater in infants of primigravida (50.7%) than in those of multigravida (27.9%). All infants received prophylactic vitamin K, and no infant with positive PIVKA-II in cord blood subsequently had clinical bleeding. Because of the high prevalence of vitamin K deficiency in newborn infants in the South of Thailand, all newborn infants should receive prophylactic vitamin K at birth.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Protein Precursors
/
Vitamin K Deficiency
/
Female
/
Humans
/
Male
/
Infant, Newborn
/
Prothrombin
/
Biomarkers
/
Fetal Blood
Language:
English
Year:
1993
Type:
Article
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