Does GnRH analog improve the final height in Thai girls with idiopathic central precocious puberty?
Article
in English
| IMSEAR
| ID: sea-44559
ABSTRACT
Ten Thai girls with idiopathic central precocious puberty (ICPP) were treated with gonadotrophin releasing hormone (GnRH) analog for a mean period of 1.5+/-0.4 years. The predicted adult height at the end of treatment was significantly higher than that at the start of treatment (158.2+/-7.9 vs 153.0+/-8.7 cm, p=0.009). In addition, treatment with GnRH analog could significantly regress the breast staging from 3.4+/-0.8 to 2.6+/-1.0 (p=0.04),but not the pubic hair staging. Five of them reached a final height which was not significantly higher than the predicted adult height before treatment (153.1+/-4.8 vs 150.7+/-1.0 cm, p=0.5). In conclusion, treatment with GnRH analog in Thai girls with ICPP can improve the predicted adult height and regress the breast staging. However, the improvement of final height is not promising.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Puberty, Precocious
/
Body Height
/
Female
/
Humans
/
Body Mass Index
/
Child
/
Anthropometry
/
Probability
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Predictive Value of Tests
/
Follow-Up Studies
Type of study:
Observational study
/
Prognostic study
Language:
English
Year:
2001
Type:
Article
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