Risk factors of hepatitis C virus infection in blood donors in Thailand: a multicenter case-control study.
Article
in English
| IMSEAR
| ID: sea-44613
ABSTRACT
OBJECTIVE:
To investigate the risk of hepatitis C virus (HCV) infection in healthy blood donors in Thailand MATERIAL ANDMETHOD:
We performed a case-control study of 435 HCV-seropositive blood donors and 894 HCV-seronegative blood donors as controls. The study was done with direct interview regarding demographic characteristics and risk factors. Odds ratios (OR) with 95% confidence intervals (CIs) were calculated by using conditional logistic regression.RESULTS:
The final multivariable model included only the following independent HCVrisk factors intravenous drug user (IDU) (OR = 61.5; 95%CI, 26.6-142.5), previous blood or blood products transfusion (OR = 12.3; 95%CI, 7.6 -19.9), sharing of razors (OR = 2.3, 95%CI, 1.6-3.2),unsafe injection (OR = 3.3, 95%CI, 1.8-5.9), unused condom (OR = 1.6; 95%CI, 1.1, 2.4). No risk was shown for a history of tattoo, ear piercing, or acupuncture and multiple sexual partners.CONCLUSION:
The risk factors for HCV infection in healthy blood donors in Thailand are IDU, past history of blood transfusion and unsafe injection.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thailand
/
Blood Donors
/
Humans
/
Case-Control Studies
/
Seroepidemiologic Studies
/
Demography
/
Cross-Sectional Studies
/
Interviews as Topic
/
Risk Factors
/
Health Surveys
Type of study:
Controlled clinical trial
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Etiology study
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Observational study
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Prevalence study
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Prognostic study
/
Qualitative research
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Year:
2006
Type:
Article
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