Seroprevalence of hepatitis A virus antibody among children and young adults in Bangkok.
Article
in English
| IMSEAR
| ID: sea-45303
ABSTRACT
OBJECTIVE:
To determine the prevalence of hepatitis A virus (HAV) antibodies in various age groups of healthy children and young adults who have not received the hepatitis A vaccine.METHOD:
Blood samples were collected from 825 volunteers aged 1-30 years from a well baby clinic and five academic institutions in the Don Mueang area from 1998 to 1999. Serum samples were assayed for specific HAV IgG antibodies using a commercial enzyme-linked immunosorbent assay (ELISA) kit.RESULTS:
The seropositivity rate (12.4% overall) in each age group was as follows 1-3 years, 7.7 per cent; 4-7 years, 6.6 per cent; 8-11 years, 12.4 per cent; 12-15 years, 10.7 per cent and 16-30 years, 25.9 per cent.CONCLUSIONS:
In the Don Mueang area of Bangkok, the majority of children (< 16 years) do not have natural immunity against HAV. The use of hepatitis A vaccine for this population should be considered. Pre-vaccination serologic screening for HAV IgG in children may not be worthwhile.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thailand
/
Female
/
Humans
/
Male
/
Enzyme-Linked Immunosorbent Assay
/
Hepatitis Antibodies
/
Chi-Square Distribution
/
Seroepidemiologic Studies
/
Child
/
Child, Preschool
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Year:
2001
Type:
Article
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