Detection of beta-thalassemia (homozygous) by hemoglobin electrophoresis on agar gel and citrate agar medium: a case report.
Article
in English
| IMSEAR
| ID: sea-46822
ABSTRACT
A seven month old male baby was admitted to NICU of BPKIHS, Dharan with dyspnoea and distress. He was investigated for hemolytic anemia and suspected of beta Thalassemia (Homozygous) based on the low level of Hb and high HbF%. To investigate further, Hb electrophoresis was carried out using agar gel and citrate agar gel at pH 8.6 and 6.0 respectively along with control. Electrophoretogram showed single narrow band lagging behind the healthy control moved toward anode at pH 8.6 and single narrow band moved parallel to healthy control toward cathode at pH 6.0. Thus the diagnosis of betaThalassemia (Homozygous) is favored.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Male
/
Fetal Hemoglobin
/
Hemoglobin A
/
Citrates
/
Beta-Thalassemia
/
Culture Media
/
Electrophoresis, Agar Gel
/
Homozygote
/
Infant
Type of study:
Diagnostic study
Language:
English
Year:
2007
Type:
Article
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