Polymorphonuclear leukocyte function in type-2 diabetes mellitus patients and its correlation with glycaemic control.
Article
in English
| IMSEAR
| ID: sea-46873
ABSTRACT
Infection is an important cause of morbidity and mortality in diabetic patients. Chronic hyperglycaemia impairs host defense mechanism such as cell mediated immunity, polymorphonuclear leukocyte (PMNL) function, antibody formation etc. PMNL serves as bodies first line of defense against various infections. The present study was undertaken to establish a correlation between impaired PMNL function, blood glucose levels and its improvement with good glycaemic control with glibenclamide and glimepiride, with special reference to parameters such as respiratory burst and O2(-) and H2O2 production by diabetic neutrophils.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Sulfonylurea Compounds
/
Blood Glucose
/
Aged
/
Female
/
Humans
/
Male
/
Glycated Hemoglobin
/
Chronic Disease
/
Respiratory Burst
/
Glyburide
Language:
English
Year:
2007
Type:
Article
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