The role of lipid profile as a risk factor indicator for ischemic stroke at Cipto Mangunkusumo Hospital, Jakarta.
Acta Med Indones
;
2006 Jan-Mar; 38(1): 11-6
Article
in English
| IMSEAR
| ID: sea-47155
ABSTRACT
AIM:
to determine the role of low HDL-cholesterol, and high total cholesterol, LDL-Cholesterol and triglyceride as risk factors for ischemic stroke at Dr. Cipto Mangunkusumo Hospital.METHOD:
a study was conducted on 76 patients with an age range of 40-70 years. Subjects consisted of 38 post ischemic stroke patients and 38 control subjects with a diagnosis other than stroke. The study sample consisted of serum for lipid profile assessment. Total cholesterol and triglyceride were assessed using enzymatic method, while HDL-cholesterol and LDL-cholesterol using direct homogenous enzymatic method. Statistical analysis was performed using chi-square and multivariate analysis using logistic regression.RESULTS:
low HDL-cholesterol was found in ischemic stroke patients and demonstrated a significant difference compared to control subjects (p<0.05). The results of total cholesterol, triglyceride, LDL-cholesterol did not demonstrate a significant difference. The odds ratio (3.09; CI 95% 1.04; 8.73) demonstrates that low HDL-cholesterol is a risk factor for ischemic stroke.CONCLUSION:
a low HDL-cholesterol level is a risk factor for ischemic stroke, with an odds ratio of 3.09, while total cholesterol, triglyceride and high LDL-cholesterol levels were not risk factors for ischemic stroke.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Triglycerides
/
Aged
/
Female
/
Humans
/
Chi-Square Distribution
/
Brain Ischemia
/
Multivariate Analysis
/
Risk Factors
/
Adult
/
Stroke
Type of study:
Etiology study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Journal:
Acta Med Indones
Year:
2006
Type:
Article
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