Serum homocysteine in pre-eclampsia and eclampsia.
Bangladesh Med Res Counc Bull
;
2008 Apr; 34(1): 16-20
Article
in English
| IMSEAR
| ID: sea-472
ABSTRACT
Pre-eclampsia and eclampsia are common obstetrical problem causing adverse effects on pregnancy outcome. Large bodies of evidences suggest that hyperhomocysteinemia is a causal factor of pre-eclampsia/eclampsia. This study designed to explore the association between hyperhomocysteinemia and pre-eclampsia/eclampsia, the knowledge of which expected to be used for prevention of pre-eclampsia and eclampsia. In a case-control study serum homocysteine was measured in 136 controls (healthy pregnant), 84 pre-eclamptic and 120 eclamptic pregnant women. Serum homocysteine in patients with pre-eclampsia (9.54 +/- 3.21 micromol/L) and eclampsia (10.57 +/- 3.39 micromol/L) found to be significantly increased compared to controls (6.86 +/- 2.47 micromol/L) (p < 0.001). Between pre-eclampsia and eclampsia, homocysteine found to be raised more in eclampsia compared to pre-eclampsia (p < 0.03). In conclusion, hyperhomocysteinemia is associated with pre-eclampsia as well as eclampsia, but in eclampsia the severity of homocysteine elevation is more compared to that in pre-eclampsia.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pre-Eclampsia
/
Bangladesh
/
Female
/
Humans
/
Pregnancy
/
Case-Control Studies
/
Pilot Projects
/
Risk Factors
/
Adult
/
Hyperhomocysteinemia
Type of study:
Etiology study
/
Observational study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Journal:
Bangladesh Med Res Counc Bull
Year:
2008
Type:
Article
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