Raised serum IgE levels in chronic inflammatory lung diseases.
Ceylon Med J
;
1995 Mar; 40(1): 14-8
Article
in English
| IMSEAR
| ID: sea-47419
ABSTRACT
OBJECTIVE:
To study the serum IgE response in nonallergic subjects with chronic inflammatory lung diseases.SETTING:
Christian Medical College Hospital, Vellore.SUBJECTS:
Twenty six patients with bronchiectasis, five with pulmonary mycosis referred from all over India and 30 healthy subjects. MAIN OUTCOMEMEASURES:
Serum IgE value (determined by radioimmuno assay) above the upper limit of normal control range (136 to 948 iu/ml) was considered as raised level.RESULTS:
Of the 26 patients with bronchiectasis 13 had pyogenic infections, six had pulmonary tuberculosis; in six patients sputum culture was sterile while another patient had herpes zoster. Five cases of mycosis included one each of actinomycosis, aspergillosis, blastomycosis, cryptococcosis and nocardiasis. The serum IgE levels were raised in 20 (65%) of the 31 patients.CONCLUSION:
Associated bacterial, fungal and parasitic infections were probably responsible for inducing an hyper-IgE response in these non-allergic subjects.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Bronchiectasis
/
Humans
/
Immunoglobulin E
/
Chronic Disease
/
Adult
/
Lung Diseases, Fungal
/
Middle Aged
Language:
English
Journal:
Ceylon Med J
Year:
1995
Type:
Article
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