Clinical features of systemic lupus erythematosus in Sri Lankan patients: results from a lupus clinic.
Ceylon Med J
;
2000 Dec; 45(4): 162-5
Article
in English
| IMSEAR
| ID: sea-48922
ABSTRACT
OBJECTIVES:
To find the common clinical features, pattern of visceral involvement, treatment received and outcome in patients diagnosed as having systemic lupus erythematosus (SLE) on American Rheumatological Association (ARA) criteria.SETTING:
Clinic for patients referred or admitted to the University Medical Unit, National Hospital of Sri Lanka, Colombo, with diagnosed or suspected SLE. DESIGN ANDMETHODS:
A prospective descriptive study. Clinical features of patients collected at time of registration in the clinic were maintained in a database. Patients were followed up prospectively and changes recorded. Data were analysed after 3 years of follow up.RESULTS:
Of the 111 patients registered during this period, 96 (86%) were clinically diagnosed as having SLE. Of these, 77 patients (80%) satisfied ARA criteria for diagnosis of SLE. 72 were females (93%). The mean age of patients who satisfied the ARA criteria was 32 years (range 11 to 58), and the mean duration of disease 7 years (range 1 to 15). The commonest presentation was with mucocutaneous features (98%) and alopecia in 87%. Systemic features were found in 92% of patients. 67 (87%) of patients had visceral involvement with 60 (78%) having it at time of diagnosis. 53 (69%) had renal, 42 (54%) haematological, 33 (42%) neurological, 12 (16%) cardiac and 8 patients pulmonary involvement. Five patients died during the 3-year follow up and 2 developed chronic renal failure. Three patients underwent successful pregnancy after diagnosis of SLE.CONCLUSIONS:
Our study confirmed the wide variability of clinical features seen in SLE. Alopecia and visceral involvement were common in Sri Lankan patients.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Sri Lanka
/
Severity of Illness Index
/
Female
/
Humans
/
Male
/
Child
/
Child, Preschool
/
Incidence
/
Survival Rate
/
Prospective Studies
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Journal:
Ceylon Med J
Year:
2000
Type:
Article
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