Primary immune deficiency among patients with recurrent infections.
Ceylon Med J
;
2007 Sep; 52(3): 83-6
Article
in English
| IMSEAR
| ID: sea-49254
ABSTRACT
OBJECTIVES:
Primary immune deficiency is relatively rare. Patients present with recurrent or persistent infections or infections with opportunistic pathogens. We investigated patients who presented during the years 2005-7 with recurrent or persistent infections or infections with opportunistic organisms, for underlying immune deficiency.DESIGN:
Descriptive study.SETTING:
Department of Immunology, Medical Research Institute, Colombo. STUDY POPULATION 257 patients referred to the Department of Immunology, Medical Research Institute, Colombo, with a history of recurrent infections, for evaluation of possible immune deficiency. MEASUREMENTS Appropriate evaluation of immunological competence of the humoral and cell mediated immune systems.RESULTS:
There were 8 patients with agammaglobulinaemia (X linked agammaglobulinaemia and autosomal recessive agammaglobulinaemia), 2 patients each with ataxia telangiectasia, IgA deficiency and hyper-IgE syndrome, 3 patients with common variable immune deficiency (CVID), and 1 patient each with Griscelli syndrome, hyper-IgM syndrome and X linked severe combined immune deficiency (SCID).CONCLUSIONS:
Primary immune deficiency must be included in the evaluation of patients with recurrent infections, and timely intervention can prevent morbidity and mortality.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Recurrence
/
Autoimmune Diseases
/
Female
/
Humans
/
Male
/
Infant, Newborn
/
Ataxia Telangiectasia
/
Child
/
Child, Preschool
/
Pilot Projects
Language:
English
Journal:
Ceylon Med J
Year:
2007
Type:
Article
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