Prevalence of prostatic intraepithelial (PIN) in surgical resections.
Indian J Cancer
;
1998 Dec; 35(4): 137-41
Article
in English
| IMSEAR
| ID: sea-49336
ABSTRACT
OBJECTIVES:
To determine the prevalence of prostatic intraepithelial neoplasia (PIN) in surgical specimens and assess its relationship to adenocarcinoma.METHOD:
205 surgical specimens (191) transurethral resections, 6 open prostatectomies, 8 needle biopsies) reported at the University Department of Pathology, Colombo over 64 months were reviewed.RESULTS:
There were 170 benign hyperplasias and 35 adenocarcinomas. PIN I was present in 22.92% PIN II in 5.36% and PIN III in 7.32% of the specimens. 8.51%, 27.27% and 93.3% PIN I, PIN II and III were associated with invasive adenocarcinoma. Nine cases (4.39%) had high grade PIN (PIN II & III) in the absence of adenocarcinoma.CONCLUSION:
PIN II & III were strongly associated with coexistent carcinoma but PIN I was not. The finding of high grade PIN in surgical biopsies with no obvious adenocarcinoma warrants examination of all available tissue and deep sections.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Prostatic Neoplasms
/
Humans
/
Male
/
Adenocarcinoma
/
Prevalence
/
Prostatic Intraepithelial Neoplasia
Type of study:
Prevalence study
/
Risk factors
Language:
English
Journal:
Indian J Cancer
Year:
1998
Type:
Article
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