Effective control of cisplatin induced emesis by combination drug regimen.
Indian J Cancer
;
1994 Mar; 31(1): 19-22
Article
in English
| IMSEAR
| ID: sea-49825
ABSTRACT
Thirty two cycles of chemotherapy were administered to sixteen patient containing 50-75 mg/msq. of cisplatin. For antiemetic prophylaxis, each patient received metoclopramide alone in the first cycle and a combination of metoclopramide + dexamethasone + lyrazepam in the next cycle. Effective control of emesis was achieved in 81% cycles on the combination antiemetic regime as compared to 19% on MCP alone. There was no statistical difference in the relief of nausea by the two regimens.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Ovarian Neoplasms
/
Vomiting
/
Remission Induction
/
Female
/
Humans
/
Dexamethasone
/
Drug Administration Schedule
/
Follow-Up Studies
/
Cisplatin
/
Adult
Type of study:
Observational study
/
Prognostic study
Language:
English
Journal:
Indian J Cancer
Year:
1994
Type:
Article
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