Current concepts in the pathology and genetics of gliomas.
Indian J Cancer
;
2009 Apr-Jun; 46(2): 108-19
Article
in English
| IMSEAR
| ID: sea-50507
ABSTRACT
In recent years, there has been a marked improvement in our understanding of molecular genetics of gliomas. These advancements offer hope for development of tailored therapies targeting a tumor's unique molecular profile, and may also translate into improved classification and identification of newer prognostic markers. This review focuses on the neuropathological features of different types of glial neoplasms according to the World Health Organization classification, and the recent advances in their molecular biology with emphasis on the genetic mechanisms underlying tumor progression, diagnostic and prognostic markers and potential therapeutic targets.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Oligodendroglioma
/
Prognosis
/
Astrocytoma
/
Brain Neoplasms
/
Humans
/
Gene Deletion
/
Glioma
Type of study:
Prognostic study
Language:
English
Journal:
Indian J Cancer
Year:
2009
Type:
Article
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