Safety and immunogenicity of the intradermal Thai red cross (2-2-2-0-1-1) post exposure vaccination regimen in the Indian population using purified chick embryo cell rabies vaccine.
Indian J Med Microbiol
;
2005 Jan; 23(1): 24-8
Article
in English
| IMSEAR
| ID: sea-53838
ABSTRACT
PURPOSE:
To test the immunogenicity of the WHO recommended "2-2-2-0-1-1" post-exposure rabies vaccination regimen in Indian subjects to determine the feasibility of replacing crude sheep brain nerve tissue rabies vaccine with modern tissue culture rabies vaccine at major anti-rabies treatment centers throughout India.METHODS:
Purified chick embryo cell vaccine (PCECV) was administered in the dosage of 0.1 mL per site to 53 Indian subjects.RESULTS:
All subjects produced rabies antibodies above 0.5 IU/mL by day 14 post-vaccination. Only minor adverse reactions including swelling (6.6%), erythema (5.4%) and pain (1.4%) were observed for which no treatment was required.CONCLUSIONS:
This study demonstrated that PCECV is safe and highly immunogenic in Indian subjects when administered intradermally as 0.1 mL/site using the "2-2-2-0-1-1" post-exposure regimen.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rabies
/
Red Cross
/
Safety
/
Thailand
/
Humans
/
Immunoglobulins
/
Injections, Intradermal
/
Rabies Vaccines
/
Chick Embryo
/
Immunization Schedule
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Med Microbiol
Journal subject:
Microbiology
Year:
2005
Type:
Article
Similar
MEDLINE
...
LILACS
LIS