Utility of beige mouse in leprosy research.
Indian J Lepr
;
1992 Oct-Dec; 64(4): 475-81
Article
in English
| IMSEAR
| ID: sea-54568
ABSTRACT
Dissemination of M. leprae to visceral organs is seen by four months onwards only in beige (C57BL/6/bgj) but not BALB/c mice following intravenous or intraperitoneal infections. Inoculation of the beige mouse derived M. leprae showed all the characteristics of M. leprae, including growth pattern in the foot-pads of BALB/c mice. M. leprae inoculated into foot-pads of beige mice multiplied faster than those in the foot-pads of BALB/c mice. The possibility of using beige mouse in chemotherapeutic studies in leprosy is discussed.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Spleen
/
Female
/
Disease Models, Animal
/
Leprosy
/
Liver
/
Animals
/
Mice
/
Mice, Inbred BALB C
/
Mice, Inbred C57BL
/
Mycobacterium leprae
Type of study:
Prognostic study
Language:
English
Journal:
Indian J Lepr
Journal subject:
Tropical Medicine
Year:
1992
Type:
Article
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