Influence of levamisole on lymphocytes and M. leprae in mice.
Indian J Lepr
;
1985 Jan-Mar; 57(1): 27-36
Article
in English
| IMSEAR
| ID: sea-54680
ABSTRACT
Normal uninfected (N) and M. leprae infected mice (NI) were given levamisole in the dose of 2.5 mg/kg body weight. The animals were observed over a period of nine months for bacillary load, T and B cell counts and blast transformation with PHA. Significant increase in B cell counts was observed in the levamisole treated normal (NL) compared to normal control (N) group. T cell counts and blast transformation, however, remained unaffected. However, T-cell counts and blast transformation improved significantly in the infected and levamisole treated (NIL) as compared to the infected group (NI) not given levamisole. Bacillary loads remained unaltered in both, the infected (NI) and levamisole treated (NIL) group.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Lymphocyte Activation
/
Lymphocytes
/
Levamisole
/
Leprosy
/
Leukocyte Count
/
Animals
/
Mice
Language:
English
Journal:
Indian J Lepr
Journal subject:
Tropical Medicine
Year:
1985
Type:
Article
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