Primary dapsone resistance as assessed by uptake of labelled thymidine by the macrophage resident Mycobacterium leprae.
Indian J Lepr
;
1989 Oct; 61(4): 437-41
Article
in English
| IMSEAR
| ID: sea-54687
ABSTRACT
12 untreated lepromatous leprosy patients were screened for primary dapsone resistance by the uptake of labelled thymidine by macrophage resident M. leprae. There were found to harbour primary dapsone resistant strains of M. leprae and another three partially resistant strains to the drug. This rapid, simple and reliable method should be used routinely to screen leprosy patients, for drug resistance.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thymidine
/
Tritium
/
Humans
/
Drug Resistance, Microbial
/
Leprosy, Lepromatous
/
Cells, Cultured
/
Dapsone
/
Macrophages
/
Mycobacterium leprae
Language:
English
Journal:
Indian J Lepr
Journal subject:
Tropical Medicine
Year:
1989
Type:
Article
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