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The mouse footpad test--sensitive to small proportions of drug-resistant bacilli in a sample of M. leprae.
Indian J Lepr ; 1984 Jan-Mar; 56(1): 10-4
Article in English | IMSEAR | ID: sea-54783
ABSTRACT
In experiments at the Radda Barnen Research Laboratories of the SLR & TC Karigiri, the mouse footpad test was demonstrated to detect DDS-resistant M.leprae even if as few as 0.1% (1 in 1000) of the M. leprae tested were DDS-resistant. The mouse footpad test appears to be sensitive to minute proportions of drug-resistant bacilli in samples of M. leprae tested.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Drug Resistance, Microbial / Microbial Sensitivity Tests / Dapsone / Animals / Mice / Mice, Inbred CBA / Mycobacterium leprae Language: English Journal: Indian J Lepr Journal subject: Tropical Medicine Year: 1984 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Drug Resistance, Microbial / Microbial Sensitivity Tests / Dapsone / Animals / Mice / Mice, Inbred CBA / Mycobacterium leprae Language: English Journal: Indian J Lepr Journal subject: Tropical Medicine Year: 1984 Type: Article