Primary dapsone resistance in leprosy.
Indian J Lepr
;
1985 Jul-Sep; 57(3): 507-13
Article
in English
| IMSEAR
| ID: sea-54994
ABSTRACT
20 carefully selected untreated patients of bacilliferous leprosy were investigated for primary dapsone resistance by foot pad inoculation. Mice were fed on 0.001 g% and 0.01 g% of dapsone during the period of study. Mice in the control group were given normal rodent feed only. Animals were sacrificed from 6 month onwards at 6 week intervals upto 9 months. In two animals the growth of M. leprae was not inhibited by 0.001 g% concentration of dapsone in diet, but was completely inhibited by 0.01 g% of dapsone.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Drug Resistance, Microbial
/
Adolescent
/
Adult
/
Dapsone
/
Foot
/
Leprosy
/
Animals
/
Mice
/
Mycobacterium leprae
Language:
English
Journal:
Indian J Lepr
Journal subject:
Tropical Medicine
Year:
1985
Type:
Article
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