Neoplastic transformation of chronic ulcers in leprosy patients--a retrospective study of 23 consecutive cases.
Indian J Lepr
;
1998 Apr-Jun; 70(2): 179-87
Article
in English
| IMSEAR
| ID: sea-55440
ABSTRACT
A retrospective analysis of chronic ulcers among leprosy patients seen over the last 20 years yielded 23 cases of neoplastic transformation. It showed a peak at the sixth decade, an incidence of 3.66/100 among hospitalised ulcer cases and male/female ratio of 1.61. Borderline tuberculoid was the most common type of leprosy involved (40%). Squamous cell carcinoma was the most common neoplasia. Its usual site was plantar ulcers. Heel ulcers showed relatively greater predeliction for malignancy (38.5%). Histopathological proof of malignancy is desirable and that may require multiple biopsies. Metastasis is rare but potentially fatal. The surgical treatment must provide a functional, trouble-free limb. Forefoot or Lisfranc's amputation for distal third ulcers and below-knee amputation for large midfoot and ulcers are procedures of choice. Wide excision may be used in select cases.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Recurrence
/
Skin Neoplasms
/
Aged
/
Female
/
Humans
/
Male
/
Carcinoma, Squamous Cell
/
Cell Transformation, Neoplastic
/
Chronic Disease
/
Incidence
Type of study:
Incidence study
/
Observational study
/
Prognostic study
Language:
English
Journal:
Indian J Lepr
Journal subject:
Tropical Medicine
Year:
1998
Type:
Article
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