Trophic changes and extensive dissemination in normal mice infected with human Mycobacterium leprae.
Indian J Lepr
;
1984 Oct-Dec; 56(4): 742-7
Article
in English
| IMSEAR
| ID: sea-55514
ABSTRACT
Closely bred Swiss albino normal mice (Lecca Strain) were inoculated in the footpad with M. leprae, at room temperature. The animals were harvested at 3, 6 and 9 months post inoculation, and bacillary counts were made. Trophic changes were observed in the tail-tips, ears, footpads and forepaws 12-14 months post inoculation in a group which was allowed to survive. The histopathological changes and bacillary infiltration was found in many tissues/organs. The possibility of studying this normal strain of mice as an experimental model for human leprosy has been discussed.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Leprosy
/
Animals
/
Mice
/
Mice, Inbred Strains
/
Mycobacterium leprae
Language:
English
Journal:
Indian J Lepr
Journal subject:
Tropical Medicine
Year:
1984
Type:
Article
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