Antidepressant activity of hyperforin conjugates of the St. John's wort, Hypericum perforatum Linn.: an experimental study.
Indian J Exp Biol
;
2001 Dec; 39(12): 1302-4
Article
in English
| IMSEAR
| ID: sea-55625
ABSTRACT
Nine extracts of H. perforatum, containing hyperforin in conjugated forms, but devoid of free hyperforin and adhyperforin, were subjected to antidepressant screening using the forced swim test (FST). The observed activity was compared with that of SJW extracts containing hyperforin and adhyperforin (in free form). Results indicate that hyperforin conjugates exhibit significant antidepressant activity as evidenced by the reduced immobility period in the FST in rats.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Phloroglucinol
/
Rats
/
Swimming
/
Terpenes
/
Bridged Bicyclo Compounds
/
Female
/
Male
/
Plant Extracts
/
Hypericum
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
2001
Type:
Article
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