Anti-platelet activating factor property of Rubia cordifolia Linn.
Indian J Exp Biol
;
1993 Jun; 31(6): 533-5
Article
in English
| IMSEAR
| ID: sea-55693
ABSTRACT
Rubia cordifolia is clinically used for the purification of blood by the physicians of the Indian System of Medicine. For the first time, the effect of the partially purified fraction of this whole plant has been studied on rabbit platelets. It inhibits the platelet aggregation induced by PAF (platelet activating factor) but not thrombin. It also inhibits the binding of 3H-PAF to the platelets in the dose-dependent manner. Thus it appears that R. cordifolia inhibits action of PAF at its receptor level either by it's blocking or by desensitization.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Plants, Medicinal
/
Rabbits
/
Blood Platelets
/
Platelet Aggregation Inhibitors
/
Plant Extracts
/
Platelet Activating Factor
/
Platelet Aggregation
/
Ethanol
/
India
/
Animals
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Exp Biol
Year:
1993
Type:
Article
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