Effect of cisplatin, rIFN-Y, LPS and MDP on release of H2O2, O2- and lysozyme from human monocytes in vitro.
Indian J Exp Biol
;
1991 Oct; 29(10): 910-5
Article
in English
| IMSEAR
| ID: sea-55777
ABSTRACT
Increased secretion of H2O2, O2- and lysozyme by human monocytes in vitro on treatment with cisplatin, rIFN-Y (interferon-Y), LPS (lipopolysaccharide) and MDP (muramyl dipeptide) is reported. It is suggested that increased production of these secretory products represent the activated state of monocytes. These in vitro activated monocytes could either kill the tumor cells via increased contact mediated cytolysis or cytolysis mediated via the release of the secretory products like H2O2, O2- and lysozyme.
Full text:
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Index:
IMSEAR (South-East Asia)
Main subject:
Peroxides
/
Time Factors
/
Recombinant Proteins
/
Humans
/
Monocytes
/
Muramidase
/
Acetylmuramyl-Alanyl-Isoglutamine
/
Lipopolysaccharides
/
Interferon-gamma
/
Cisplatin
Language:
English
Journal:
Indian J Exp Biol
Year:
1991
Type:
Article
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