Protective role of allicin and L-ascorbic acid against the genotoxic damage induced by chlormadinone acetate in cultured human lymphocytes.
Indian J Exp Biol
;
2005 Sep; 43(9): 769-72
Article
in English
| IMSEAR
| ID: sea-55846
ABSTRACT
In our present study, different doses of allicin and L-ascorbic acid were tested against the genotoxic damage induced by chlormadinone acetate (CMA; 40 microM) using chromosomal aberrations (CAs) and sister chromatid exchanges (SCEs) as the parameters. Treatment with allicin and L-ascorbic acid resulted in reduction of CAs and SCEs. The results suggested a protective role of allicin and L-ascorbic acid against CMA induced genotoxic damage.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Ascorbic Acid
/
Sister Chromatid Exchange
/
Sulfinic Acids
/
Time Factors
/
Humans
/
Lymphocytes
/
Cells, Cultured
/
Chlormadinone Acetate
/
Free Radical Scavengers
/
Chromosome Aberrations
Type of study:
Prognostic study
Language:
English
Journal:
Indian J Exp Biol
Year:
2005
Type:
Article
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