Hypoglycemic activity of Swertia chirayita (Roxb ex Flem) Karst.
Indian J Exp Biol
;
1990 Jul; 28(7): 616-8
Article
in English
| IMSEAR
| ID: sea-56294
ABSTRACT
Hexane fraction of S. chirayita (250 mg/kg body wt.) induced significant fall in blood sugar and significant increase in plasma IRI simultaneously after single oral administration without influencing liver glycogen concentration in albino rats. On the other hand, daily administration for 28 days resulted in significant lowering of blood sugar and increase in plasma IRI along with a significant rise in liver glycogen. Intestinal absorption of glucose was not inhibited by hexane fraction. It is suggested that hexane fraction of S. chirayita possibly acts through its insulin releasing effect.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Secretory Rate
/
Male
/
Plant Extracts
/
Glucose
/
Hypoglycemia
/
Insulin
/
Intestinal Absorption
/
Liver Glycogen
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
1990
Type:
Article
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