Antiviral profile of Nyctanthes arbortristis L. against encephalitis causing viruses.
Indian J Exp Biol
;
2005 Dec; 43(12): 1156-60
Article
in English
| IMSEAR
| ID: sea-56346
ABSTRACT
The ethanolic extracts, various fractions and two pure compounds isolated from the plant N. arbortris were tested against Encephalomyocarditis Virus (EMCV) and Semliki Forest Virus (SFV). Pronounced in vitro virus inhibitory activity was observed with the ethanolic and n-butanol fractions as well as with the pure compounds arbortristoside A and arbortristoside C. In addition, ethanolic extracts and n-butanol fraction protected EMCV infected mice to the extent of 40 and 60% respectively against SFV at a daily dose of 125 mg/kg body weight.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Seeds
/
Semliki forest virus
/
Vero Cells
/
Plant Extracts
/
Chlorocebus aethiops
/
Administration, Oral
/
Cardiovirus Infections
/
Alphavirus Infections
/
1-Butanol
/
Oleaceae
Language:
English
Journal:
Indian J Exp Biol
Year:
2005
Type:
Article
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