Response of liver antioxidant system to taurine in rats fed high fructose diet.
Indian J Exp Biol
;
2002 Sep; 40(9): 1016-9
Article
in English
| IMSEAR
| ID: sea-56710
ABSTRACT
Fructose-fed rats were more susceptible to peroxidative damage as measured by thiobarbituric acid reactive species. The concentrations of lipid peroxides, diene conjugates, lipofuscin and hydroperoxides were significantly higher. The levels of enzymic antioxidants such as vitamin C, vitamin E and glutathione and activities of antioxidant enzymes were significantly lower in fructose-fed rats. When these rats received taurine in drinking water, peroxidative damage was minimal in both plasma and liver. Taurine was effective in inducing the antioxidant potential in fructose-fed rats. Increased peroxidative damage in liver is likely to be associated with fructose dependent pathology, which could be reduced by taurine by enhancing the antioxidant potential.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Ascorbic Acid
/
Rats
/
Superoxide Dismutase
/
Taurine
/
Vitamin E
/
Male
/
Catalase
/
Thiobarbituric Acid Reactive Substances
/
Rats, Wistar
/
Diet
Language:
English
Journal:
Indian J Exp Biol
Year:
2002
Type:
Article
Similar
MEDLINE
...
LILACS
LIS