Comparative immunopotentiating properties of saponin and incomplete Freund's adjuvant coupled to affinity purified larval antigen of Hyalomma anatolicum anatolicum.
Indian J Exp Biol
;
2002 Sep; 40(9): 1026-31
Article
in English
| IMSEAR
| ID: sea-57021
ABSTRACT
Comparative immunostimulatory properties of saponin and incomplete Freund's adjuvant (IFA) were studied using affinity purified 39 kDa larval antigen of Hyalomma anatolicum anatolicum. Significant antibody response to 39 kDa antigen was detected in the sera of rabbits immunized with both 39 kDa plus saponin and 39 kDa plus IFA in comparison to their corresponding control animals. Insignificant differences were noted in the antibody response between the animals of two immunized groups. Upon challenge, the animals immunized with 39 kDa plus IFA rejected 76.2 +/- 9.7% of larvae and 45.8 +/- 4.1% of adults while in group of animals injected with 39 kDa plus saponin rejected 80.9 +/- 11.2% of larvae and 47.2 +/- 5.7% of adults.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rabbits
/
Saponins
/
Ticks
/
Immunoglobulin G
/
Cattle
/
Freund's Adjuvant
/
Immunotoxins
/
Chromatography, Affinity
/
Immunization
/
Immune Sera
Language:
English
Journal:
Indian J Exp Biol
Year:
2002
Type:
Article
Similar
MEDLINE
...
LILACS
LIS