Effects of deltamethrin on granule cell migration during postnatal development of rat cerebellum.
Indian J Exp Biol
;
2005 Feb; 43(2): 158-62
Article
in English
| IMSEAR
| ID: sea-57189
ABSTRACT
Deltamethrin (DLT; 0.7mg/kg/body wt/day, i.p., dissolved in propylene glycol) administration during postnatal days 913 in Albino rat pups, resulted in a delayed appearance of radial glial fibers, that guide the migration of granule cells. Moreover, the radial glial fibers in the DLT-treated pups were disorganized, hypertrophied and heavily stained. Thus, it is being proposed that although after exposure to DLT the neuronal proliferation occurs at normal rate, the neuronal migration along the stumpy and crumpled radial fibers hamper the journey of the healthy neurons to their proper destination.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pyrethrins
/
Rats
/
Immunohistochemistry
/
Cell Movement
/
Cerebellum
/
Neuroglia
/
Rats, Wistar
/
Glial Fibrillary Acidic Protein
/
Insecticides
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
2005
Type:
Article
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