Anticholestatic effect of picroliv, active hepatoprotective principle of Picrorhiza kurrooa, against carbon tetrachloride induced cholestasis.
Indian J Exp Biol
;
1993 Apr; 31(4): 316-8
Article
in English
| IMSEAR
| ID: sea-57257
ABSTRACT
Picroliv showed a dose (3-12 mg/kg, po for 7 days) dependent choleretic activity as evidenced by increase in bile flow and its contents (bile salts and bile acids). Significant anticholestatic activity was also observed against carbon tetrachloride induced cholestasis in conscious rat, anaesthetized guinea pig and cat. Picroliv was more active than the known hepatoprotective drug silymarin.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Silymarin
/
Vanillic Acid
/
Female
/
Male
/
Bile Acids and Salts
/
Carbon Tetrachloride
/
Plant Extracts
/
Cats
/
Cholestasis
Language:
English
Journal:
Indian J Exp Biol
Year:
1993
Type:
Article
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