Testicular lactate dehydrogenase and sorbitol dehydrogenase activity after intratesticular injection of dynorphin and morphine in male rats.
Indian J Exp Biol
;
1996 Apr; 34(4): 363-5
Article
in English
| IMSEAR
| ID: sea-57262
ABSTRACT
Testicular lactate dehydrogenase (LDH) and sorbitol dehydrogenase (SDH) activity were measured at 1 and 4 hr following intratesticular injection of morphine and dynorphin. Twenty five and 50 micrograms doses of morphine sulfate significantly reduced LDH activity at 1 hr after injection. Five and 25 micrograms doses of dynorphin reduced LDH activity both at 1 and 4 hr after treatment. Testicular SDH activity was increased by morphine at 1 hr followed by a decrease at 4 hr. Both doses of dynorphin significantly reduced SDH activity at 1 and 4 hr after treatment. These results indicate paracrine regulatory role for opioids in testicular metabolism.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Testis
/
Male
/
Dynorphins
/
Rats, Wistar
/
Analgesics, Opioid
/
L-Iditol 2-Dehydrogenase
/
L-Lactate Dehydrogenase
/
Animals
/
Microinjections
Language:
English
Journal:
Indian J Exp Biol
Year:
1996
Type:
Article
Similar
MEDLINE
...
LILACS
LIS