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Beta-adrenergic modulation of rat brain insulin receptor activity in normal and hyperglycaemic conditions.
Indian J Exp Biol ; 1994 Feb; 32(2): 92-4
Article in English | IMSEAR | ID: sea-57295
ABSTRACT
The [125I]Insulin binding and receptor kinase activity were assessed in rat brain in the presence of 10 microM concentrations of the beta agonist isoproterenol. While insulin binding remained unaltered, beta agonist treatment enhanced significantly receptor kinase activity in control and hyperglycaemic conditions. Antihyperglycaemic effects of isoproterenol were discussed in relation to adrenergic effects on insulin action in brain.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Phosphotransferases / Rats / Reference Values / Brain / Male / Receptor, Insulin / Rats, Wistar / Hyperglycemia / Isoproterenol / Animals Language: English Journal: Indian J Exp Biol Year: 1994 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Phosphotransferases / Rats / Reference Values / Brain / Male / Receptor, Insulin / Rats, Wistar / Hyperglycemia / Isoproterenol / Animals Language: English Journal: Indian J Exp Biol Year: 1994 Type: Article