In vitro effects of organophosphate pesticides on rat erythrocytes.
Indian J Exp Biol
;
2004 Mar; 42(3): 292-6
Article
in English
| IMSEAR
| ID: sea-57420
ABSTRACT
In vitro effects of various organophosphate pesticides (dimethoate, chlorpyrifos, ethion and monocrotophos) were studied on hemolysis, K+ leakage and lipid peroxidation in rat erythrocytes. All the four pesticides increased hemolysis and K+ leakage from erythrocytes, that was concentration and time dependent. On the contrary, there was decrease in lipid peroxidation in erythrocyte membrane. Effect of pesticides on lipid peroxidation could be due to pesticide itself abstracting protons or interacting with free radicals rather than polyunsaturated fatty acids (PUFA), thereby protecting the latter against peroxidation.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Organophosphorus Compounds
/
Pesticides
/
Potassium
/
Rats
/
Time Factors
/
Male
/
Lipid Peroxidation
/
Erythrocytes
/
Fatty Acids, Unsaturated
/
Hemolysis
Language:
English
Journal:
Indian J Exp Biol
Year:
2004
Type:
Article
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