Dietary hexachlorocyclohexane induced changes in blood and liver lipids in albino mice.
Indian J Exp Biol
;
1990 Feb; 28(2): 155-7
Article
in English
| IMSEAR
| ID: sea-57670
ABSTRACT
Dietary intake of technical hexachlorocyclohexane (HCH) by albino mice for 2 weeks (at 400 and 800 ppm) resulted in hyperlipemia. Significant increase in triglycerides, phospholipids and cholesterol fractions of blood was observed in these animals. Dietary intake of gamma-isomer of HCH for 2 weeks (at 200 ppm) did not have any effect on blood lipid profile, but at 400 ppm level produced higher contents of phospholipids and cholesterol. The hepatomegaly produced by dietary technical HCH or gamma-HCH was not accompanied by fatty metamorphosis of liver. Hypertriglyceridemia caused by HCH was accompanied by lower triglyceride levels in liver, suggesting a possible higher rate of secretion from liver.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Phospholipids
/
Triglycerides
/
Hexachlorocyclohexane
/
Male
/
Cholesterol
/
Administration, Oral
/
Lipid Metabolism
/
Lipids
/
Liver
/
Animals
Language:
English
Journal:
Indian J Exp Biol
Year:
1990
Type:
Article
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